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Filtered Search Results
[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 10mg | 445408910](https://assets.fishersci.com/TFS-Assets/CCG/product-images/502183528.JPG-250.jpg)
eMolecules 863971-12-4 | MMAF-methyl ester | Broadpharm | MFCD30535529 | 746.003 | C40H67N5O8 | 98.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 10mg | 445408910
MMAF-methyl ester | Broadpharm | 863971-12-4 | MFCD30535529 | 746.003 | C40H67N5O8 | 98.000 | CC[C@H](C)[C@@H]([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC)OC)N(C)C(=O)[C@@H](NC(=O)[C@@H](NC)C(C)C)C(C)C | 10mg | 445408910
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Apexbio Technology LLC CA 074 134448-10-5 1mg
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CA 074 (CAS 134448-10-5) is a selective inhibitor of cathepsin B a cysteine protease involved in diverse pathological mechanisms By targeting cathepsin B CA 074 alleviates neurotoxicity induced by amyloid-activated microglia and inhibits proteolytic cascades associated with cell growth suppression and plasminogen activation Additionally CA 074 treatment modulates immune responses by shifting CD4 T cells from a Th2 to a Th1 phenotype reducing IgE and IgG1 levels In vivo studies indicate that CA 074 can attenuate TNF- -induced hepatic injury highlighting its relevance as a research tool in inflammation immunology and neurodegenerative disease investigations
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Accela Chembio Inc Methyl 3-nitrophenylacetate | 5g | 10268-12-9 | MFCD08669939 | 97+% | Shelf Life: 540 Days | Regular
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Methyl 3-nitrophenylacetate | 5g | 10268-12-9 | MFCD08669939 | 97+% | Shelf Life: 540 Days | Regular
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Medchemexpress LLC N-(3-propylcarbamoyloxirane-2-carbonyl)-isoleucyl-proline | 134448-10-5 | MFCD00797531 | >98.0% | 383.44 g/mol | C18H29N3O6 | 100 MG
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CA-074 is a potent, selective inhibitor of cathepsin B with a reported Ki of 2-5 nM, used in biochemical and cell-based research to study cysteine protease activity. It is an epoxysuccinyl peptide derivative with typical purity over 98% and a molecular weight of 383.44 g/mol.
- Potent cathepsin B inhibition with Ki of 2-5 nM.
- Suitable for biochemical and cell-based assays.
- Typical purity greater than 98% (HPLC).
- Molecular formula C18H29N3O6 and molecular weight 383.44 g/mol.
- Available in multiple pack sizes, including 100 MG, for research use.
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Medchemexpress LLC CA-074 methyl ester | 147859-80-1 | MFCD03452890 | 99.2% | 397.47 g·mol⁻1 | C19H31N3O6 | 100 MG
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CA-074 methyl ester is a selective, cell-permeable inhibitor of cathepsin B used in biochemical and cellular research to probe cathepsin-mediated pathways. It is commonly used in studies of neuroprotection, cancer biology, and inflammation where targeted inhibition of cathepsin B activity is required.
- Selective inhibition of cathepsin B in biochemical assays.
- Cell-permeable to enable intracellular targeting in cell-based studies.
- High purity suitable for analytical and research applications.
- Comes with supporting documentation including a datasheet and COA.
- Available in multiple pack sizes to accommodate different experimental needs.
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![Medchemexpress LLC N-[[3S-[(propylamino)carbonyl]-2S-oxiranyl]carbonyl]-L-isoleucyl-L-proline | 134448-10-5 | MFCD00797531 | >98.0% | 383.44 g/mol | C18H29N3O6 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000244730.png-250.jpg)
Medchemexpress LLC N-[[3S-[(propylamino)carbonyl]-2S-oxiranyl]carbonyl]-L-isoleucyl-L-proline | 134448-10-5 | MFCD00797531 | >98.0% | 383.44 g/mol | C18H29N3O6 | 50 MG
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CA-074 is a potent, selective inhibitor of cathepsin B with a reported Ki of 2-5 nM (CAS 134448-10-5). It is supplied as a research-grade solid for biochemical and cell-based studies of cathepsin B-dependent processes.
- Potent inhibitor of cathepsin B (Ki = 2-5 nM).
- High purity by HPLC (>98%).
- Molecular weight 383.44 g/mol.
- Chemical formula C18H29N3O6.
- White to off-white powder appearance.
- Intended for research use only.
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eMolecules 1949-55-9 | Methyl 3,5-diaminobenzoate | Combi-Blocks, Inc. | MFCD00041433 | 166.180 | C8H10N2O2 | 98.000 | COC(=O)c1cc(N)cc(N)c1 | 1g | 569292570
Methyl 3,5-diaminobenzoate | Combi-Blocks, Inc. | 1949-55-9 | MFCD00041433 | 166.180 | C8H10N2O2 | 98.000 | COC(=O)c1cc(N)cc(N)c1 | 1g | 569292570
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Medchemexpress LLC PTP1B-IN-4 100 mg
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PTP1B-IN-4 100MG
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Medchemexpress LLC Silvestrol | 697235-38-4 | >98.0% | C34H38O13 | 10MG
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Silvestrol is a natural product isolated from Agave americana that inhibits eukaryotic translation initiation factor 4A (eIF4A) and is used as a research reagent to study translation regulation, autophagy, and apoptosis.
- Inhibits eIF4A-mediated translation.
- Induces autophagy and caspase-mediated apoptosis.
- Exhibits cytotoxic activity in human cancer cell lines.
- Supplied as a powder for research use.
- Purity >98.0%.
- Available in small pack sizes (1 mg-10 mg).
- Recommended storage: powder -20°C (3 years) or 4°C (2 years).
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Medchemexpress LLC Ptp1B-In-3 1Mg | HY-15133-1MG
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Ptp1B-In-3 1Mg
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eMolecules 89-91-8 | Methyl dimethoxyacetate | Oakwood Chemical | MFCD00008484 | 134.131 | C5H10O4 | 95.000 | COC(OC)C(=O)OC | 1g | 537661484
Methyl dimethoxyacetate | Oakwood Chemical | 89-91-8 | MFCD00008484 | 134.131 | C5H10O4 | 95.000 | COC(OC)C(=O)OC | 1g | 537661484
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Medchemexpress LLC Z-WEHD-FMK | 210345-00-9 | 98.0% | 763.77 | 10 MG
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Z-WEHD-FMK is a potent, cell-permeable, and irreversible caspase-1/5 inhibitor. It also exhibits a robust inhibitory effect on cathepsin B activity (IC50=6 μM) and can be used to investigate cells for evidence of apoptosis.
- Potent, cell-permeable and irreversible caspase-1/5 inhibitor
- Exhibits robust inhibitory effect on cathepsin B activity
- Can be used to investigate cells for evidence of apoptosis
- Elicits near-complete blockage of C. trachomatis-induced cleavage of golgin-84
- Inhibits E. piscicida-induced ZF4 cells cytotoxicity and pyroptotic morphology
- Significantly induces a decrease in IL-1β release in bone marrow-derived macrophages
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Medchemexpress LLC HY-15876 5mg Medchemexpress, Clopidogrel thiolactone CAS:1147350-75-1 Purity:>98%
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Medchemexpress, HY-15876 5mg Clopidogrel thiolactone CAS:1147350-75-1 Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.
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Medchemexpress LLC [L-3-trans-(propylcarbamoyl)oxirane-2-carbonyl]-L-isoleucyl-L-proline | 134448-10-5 | MFCD00797531 | ≥95.0% | 383.44 g·mol⁻¹ | C18H29N3O6 | 1 ML
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CA-074 is a potent, selective inhibitor of cathepsin B (Ki = 2-5 nM) commonly supplied as a 10 mM solution in DMSO for use in biochemical and cellular research. The compound has molecular formula C18H29N3O6 and a molecular weight of 383.44 g·mol⁻¹.
- Potent cathepsin B inhibition with Ki = 2-5 nM.
- Supplied as a 10 mM solution, 1 mL vial, ready for in vitro use.
- Soluble in DMSO; example in vitro stock concentrations provided by the manufacturer.
- Storage guidance: powder -20 °C; in solvent -80 °C (up to 6 months) or -20 °C (up to 1 month).
- Molecular formula C18H29N3O6; molecular weight 383.44 g·mol⁻¹.
- Intended for research use only (not for human or veterinary use).
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TARGETMOL CHEMICALS INC CA-074 METHYL ESTER 5MG
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Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. CA-074 methyl ester (Cathepsin B Inhibitor IV) is a specific inhibitor of Cathepsin B with neuroprotective anti-cancer and anti-inflammatory effects. purity: 99%
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